| Primary Identifier | MGI:2444848 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 217057 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable aminoacyl-tRNA hydrolase activity. Predicted to be involved in negative regulation of anoikis; negative regulation of gene expression; and positive regulation of anoikis. Located in mitochondrion. Is expressed in embryo. Orthologous to human PTRH2 (peptidyl-tRNA hydrolase 2). PHENOTYPE: Mice homozygous for a knock-out allele display neutropenia, delayed kidney and muscle development, and postnatal death due to a runting syndrome associated with progressive muscle weakness, ataxia, and decreased weight. Cultured mouse embryonic fibroblasts show increased resistance to anoikis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
