Primary Identifier | MGI:2685585 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 327992 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables DNA-binding transcription activator activity and DNA-binding transcription repressor activity. Involved in male meiotic nuclear division and spermatogenesis. Located in XY body and nucleus. Orthologous to human HSF5 (heat shock transcription factor 5). PHENOTYPE: Homozygous null males are infertile, with small testes, arrest of spermatogenesis during meiosis with sex chromosome defects and azoospermia. [provided by MGI curators] |