Primary Identifier | MGI:1923876 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 76626 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables poly(U) RNA binding activity. Involved in stem cell development. Located in cytoplasm. Is expressed in several structures, including central nervous system; gonad; hair follicle; limb bud; and sensory organ. Orthologous to human MSI2 (musashi RNA binding protein 2). PHENOTYPE: Mice homozygous for a gene trapped allele exhibit lethality, decreased body size, and decreased hematopoietic stem cells. Mice homozygous for a conditional knock-out allele exhibit impaired hematopoietic stem cell physiology upon induction. [provided by MGI curators] |