| Primary Identifier | MGI:97356 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 18103 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable several functions, including G-quadruplex DNA binding activity; anion binding activity; and kinase activity. Predicted to be involved in several processes, including integrin-mediated signaling pathway; negative regulation of myeloid leukocyte differentiation; and ribonucleoside triphosphate biosynthetic process. Located in mitochondrion and myelin sheath. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Human ortholog(s) of this gene implicated in teratoma. Orthologous to several human genes including NME2 (NME/NM23 nucleoside diphosphate kinase 2). PHENOTYPE: Mice homozygous for a gene trapped allele exhibit impaired Th1 and Th2 cell KCa3.1 channel activity and TCR-stimulated calcium ion flux and cytokine production. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
