Primary Identifier | MGI:2669209 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 278507 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable receptor antagonist activity and transforming growth factor beta binding activity. Acts upstream of or within several processes, including muscle cell development; roof of mouth development; and transforming growth factor beta receptor signaling pathway. Located in extracellular space. Is expressed in several structures, including central nervous system; genitourinary system; limb; liver; and spleen. Orthologous to human WFIKKN2 (WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2). PHENOTYPE: Mice homozygous for a null mutation show impaired muscle regeneration and a mild decrease in skeletal muscle weight in males. [provided by MGI curators] |