| Primary Identifier | MGI:94903 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 13393 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and chromatin binding activity. Involved in several processes, including cell surface receptor signaling pathway; epithelial cell differentiation; and hair follicle cell proliferation. Acts upstream of or within blood vessel development; odontogenesis of dentin-containing tooth; and placenta development. Located in cytoplasm and nucleus. Is expressed in several structures, including brain; branchial arch; genitourinary system; jaw; and sensory organ. Human ortholog(s) of this gene implicated in amelogenesis imperfecta type 4 and trichodontoosseous syndrome. Orthologous to human DLX3 (distal-less homeobox 3). PHENOTYPE: Homozygous null mutants die at embryonic day 9.5-10.0 with defects in the labyrinthine trophoblast of the chorioallantoic placenta. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
