Primary Identifier | MGI:2182799 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 217127 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables histone H3K14 acetyltransferase activity. Involved in several processes, including lymphocyte differentiation; positive regulation of erythrocyte differentiation; and positive regulation of macromolecule biosynthetic process. Located in nucleus. Part of histone H3-K14 acetyltransferase complex. Is expressed in central nervous system; early conceptus; genitourinary system; and limb. Orthologous to human KAT7 (lysine acetyltransferase 7). PHENOTYPE: Mice homozygous for a knock-out allele exhibit embryonic growth arrest, incomplete embryo turning, disorganized yolk sac vascular plexus, and increased apoptosis. [provided by MGI curators] |