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Protein Coding Gene : Hoxb7 homeobox B7

Primary Identifier  MGI:96188 Organism  mouse, laboratory
Chromosome  11 NCBI Gene Number  15415
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables DNA binding activity. Involved in positive regulation of branching involved in ureteric bud morphogenesis. Acts upstream of or within anterior/posterior pattern specification; embryonic skeletal system morphogenesis; and myeloid cell differentiation. Predicted to be located in cytosol and nuclear body. Predicted to be active in nucleus. Is expressed in several structures, including embryo mesenchyme; genitourinary system; gut; nervous system; and neural ectoderm. Orthologous to human HOXB7 (homeobox B7).
PHENOTYPE: Homozygotes for a targeted null mutation exhibit first and second rib defects. [provided by MGI curators]
  • synonyms:
  • MGI:2144127,
  • homeobox B7,
  • Hox-2.3,
  • expressed sequence AI325018,
  • Hoxb7,
  • homeo box-2 cluster, gene 3,
  • AI325018,
  • MGD-MRK-10889,
  • MGD-MRK-10831

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

1 Genomic Clusters

3 Involved In Mutations

0 Strain

0 Transcripts

2 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

1 Driver For