Primary Identifier | MGI:96188 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 15415 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables DNA binding activity. Involved in positive regulation of branching involved in ureteric bud morphogenesis. Acts upstream of or within anterior/posterior pattern specification; embryonic skeletal system morphogenesis; and myeloid cell differentiation. Predicted to be located in cytosol and nuclear body. Predicted to be active in nucleus. Is expressed in several structures, including embryo mesenchyme; genitourinary system; gut; nervous system; and neural ectoderm. Orthologous to human HOXB7 (homeobox B7). PHENOTYPE: Homozygotes for a targeted null mutation exhibit first and second rib defects. [provided by MGI curators] |