| Primary Identifier | MGI:1101358 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 19155 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable metalloaminopeptidase activity; peptide binding activity; and zinc ion binding activity. Predicted to be involved in cellular response to hypoxia; peptide catabolic process; and proteolysis. Predicted to be located in cytosol. Predicted to be active in cytoplasm; extracellular space; and membrane. Is expressed in several structures, including alimentary system; central nervous system; ear; genitourinary system; and integumental system. Orthologous to human NPEPPS (aminopeptidase puromycin sensitive). PHENOTYPE: Homozygotes for a gene-trapped mutation exhibit dwarfism, increased anxiety, decreased pain sensitivity, and infertility in both sexes. Females fail to produce the corpus luteum of pregnancy, while males fail to copulate and have impaired spermatogenesis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
