| Primary Identifier | MGI:2384150 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 353155 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling and monoatomic ion channel activity. Involved in negative regulation of cell communication by electrical coupling involved in cardiac conduction and regulation of heart contraction. Located in gap junction. Part of connexin complex. Is expressed in atrioventricular canal; atrioventricular node; and heart. Orthologous to human GJD3 (gap junction protein delta 3). PHENOTYPE: Mice homozygous for a knock-out allele exhibit accelerated atrioventricular nodal conduction velocity in the heart but no significant alterations in excitability or fast network oscillations in the hippocampus. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
