| Primary Identifier | MGI:1927347 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 57376 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables RNA binding activity. Acts upstream of or within neurogenesis. Part of SWI/SNF complex; nBAF complex; and npBAF complex. Is expressed in several structures, including alimentary system; branchial arch; central nervous system; genitourinary system; and sensory organ. Human ortholog(s) of this gene implicated in Coffin-Siris syndrome 5; familial meningioma; and meningioma. Orthologous to human SMARCE1 (SWI/SNF related BAF chromatin remodeling complex subunit E1). PHENOTYPE: Homozygous deletion of this gene causes prenatal lethality. Mice homozygous for a knock-out allele show abnormal embryo morphology, partial embryonic death before implantation, and complete lethality by E9.5. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
