Primary Identifier | MGI:1918060 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 70810 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable protein heterodimerization activity. Acts upstream of or within hair follicle morphogenesis and intermediate filament organization. Predicted to be located in keratin filament. Predicted to be active in cytoskeleton. Is expressed in naris; oral epithelium; and vibrissa. Human ortholog(s) of this gene implicated in autosomal recessive woolly hair 3. Orthologous to human KRT25 (keratin 25). PHENOTYPE: Mutations in this gene have a defect in hair formation resulting in a wavy coat and curly vibrissae. Some alleles may compromise normal growth. [provided by MGI curators] |