Primary Identifier | MGI:109364 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 16673 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) A structural constituent of skin epidermis. Involved in regulation of keratinocyte differentiation. Located in intermediate filament cytoskeleton. Is expressed in several structures, including cranium; fronto-nasal process; skin; surface ectoderm; and tongue. Orthologous to human KRT36 (keratin 36). PHENOTYPE: Mice homozygous for a knock-out allele exhibit hyperkeratosis affecting the scales of the tail skin and the filiform papillae of the tongue. [provided by MGI curators] |