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Protein Coding Gene : Psmc3ip proteasome (prosome, macropain) 26S subunit, ATPase 3, interacting protein

Primary Identifier  MGI:1098610 Organism  mouse, laboratory
Chromosome  11 NCBI Gene Number  19183
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable several functions, including DNA binding domain binding activity; nuclear receptor binding activity; and nuclear receptor coactivator activity. Predicted to be involved in meiosis I and positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleoplasm. Predicted to be part of DNA recombinase auxiliary factor complex. Predicted to be active in condensed nuclear chromosome. Is expressed in metanephros; submandibular gland primordium; telencephalon ventricular layer; tooth; and vibrissa. Human ortholog(s) of this gene implicated in ovarian dysgenesis 3. Orthologous to human PSMC3IP (PSMC3 interacting protein).
PHENOTYPE: Homozygotes for targeted null mutations are mice were viable, showed no overt anatomical defects in somatic tissues, but are infertile in both sex due to absence of gametes. [provided by MGI curators]
  • synonyms:
  • MGI:2144650,
  • expressed sequence C79099,
  • proteasome (prosome, macropain) 26S subunit, ATPase 3, interacting protein,
  • HOP2,
  • Tbpip,
  • Psmc3ip,
  • C79099

Features --> Cross References

Genome

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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0 Driver For