Primary Identifier | MGI:1098610 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 19183 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable several functions, including DNA binding domain binding activity; nuclear receptor binding activity; and nuclear receptor coactivator activity. Predicted to be involved in meiosis I and positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleoplasm. Predicted to be part of DNA recombinase auxiliary factor complex. Predicted to be active in condensed nuclear chromosome. Is expressed in metanephros; submandibular gland primordium; telencephalon ventricular layer; tooth; and vibrissa. Human ortholog(s) of this gene implicated in ovarian dysgenesis 3. Orthologous to human PSMC3IP (PSMC3 interacting protein). PHENOTYPE: Homozygotes for targeted null mutations are mice were viable, showed no overt anatomical defects in somatic tissues, but are infertile in both sex due to absence of gametes. [provided by MGI curators] |