Primary Identifier | MGI:99924 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 217212 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables neuropeptide hormone activity. Acts upstream of or within eating behavior. Located in extracellular space. Is expressed in brain and gut. Orthologous to several human genes including PYY (peptide YY). PHENOTYPE: Mice homozygous for one null mutation showed normal growth, food intake, and energy expenditure. Mice homozygous for another null allele exhibit polyphagia, increased adipose tissue and are resistant to the benefits of a high-protein diet. [provided by MGI curators] |