| Primary Identifier | MGI:1888513 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 57265 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables Wnt receptor activity. Acts upstream of or within several processes, including hard palate development; heart morphogenesis; and inner ear development. Predicted to be located in cytoplasm. Predicted to be active in plasma membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; heart and pericardium; and sensory organ. Human ortholog(s) of this gene implicated in omodysplasia 2. Orthologous to human FZD2 (frizzled class receptor 2). PHENOTYPE: About 50% of mice homozygous for a reporter allele display a cleft palate and die as neonates; the remaining 50% survive exhibiting a variable degree of postnatal runting and reduced olfactory sensitivity to various odorants. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
