Primary Identifier | MGI:2686410 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 268491 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Involved in several processes, including germ cell development; germline cell cycle switching, mitotic to meiotic cell cycle; and meiosis I. Located in cytoplasm and nucleus. Is expressed in several structures, including gut; liver; lung; reproductive system; and spleen. Orthologous to human MEIOC (meiosis specific with coiled-coil domain). PHENOTYPE: Mice homozygous for a knock-out allele exhibit infertility with small gonads, absent germ cells and arrested meiosis. [provided by MGI curators] |