| Primary Identifier | MGI:102579 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 18107 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables glycylpeptide N-tetradecanoyltransferase activity. Acts upstream of or within N-terminal protein myristoylation and in utero embryonic development. Predicted to be located in cytoplasm and plasma membrane. Predicted to be active in cytosol. Is expressed in several structures, including central nervous system; genitourinary system; gut; hemolymphoid system gland; and liver. Orthologous to human NMT1 (N-myristoyltransferase 1). PHENOTYPE: Homozygous mutation of this gene results in embryonic lethality between E3.5 and E7.5. Heterozygotes show partial prenatal lethality. Mice homozygous for a conditional allele knocked out in T cells exhibit reduced T cell, double positive T cell and single positive T cell numbers. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
