| Primary Identifier | MGI:95768 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 14674 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable D5 dopamine receptor binding activity; G protein activity; and G-protein beta/gamma-subunit complex binding activity. Involved in adenylate cyclase-modulating G protein-coupled receptor signaling pathway; regulation of blood pressure; and regulation of postsynapse assembly. Acts upstream of or within several processes, including Rho protein signal transduction; branching involved in blood vessel morphogenesis; and platelet activation. Located in cytoplasm and nucleus. Is active in postsynapse. Is expressed in several structures, including branchial arch; genitourinary system; gut gland; nervous system; and sensory organ. Orthologous to human GNA13 (G protein subunit alpha 13). PHENOTYPE: Mice homozygous for a targeted null or with an endothelial specific conditional mutation fail to develop an organized vascular system in the yolk sac, show impaired vascular development in some vascular beds in the embryo proper, and die during organogenesis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
