| Primary Identifier | MGI:1351668 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 27404 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable ABC-type xenobiotic transporter activity and lipid transporter activity. Predicted to be involved in several processes, including cholesterol efflux; positive regulation of cholesterol efflux; and sphingomyelin biosynthetic process. Predicted to act upstream of or within xenobiotic transmembrane transport. Located in basolateral plasma membrane. Is expressed in several structures, including alimentary system; eye; limb; male reproductive gland or organ; and nervous system. Orthologous to human ABCA8 (ATP binding cassette subfamily A member 8). PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased circulating HDL cholesterol levels on a high-cholesterol diet compared with wild-type mice. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
