Primary Identifier | MGI:2443411 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 217303 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables phosphatase binding activity. Acts upstream of or within negative regulation of secretion by cell; receptor-mediated endocytosis; and serotonin secretion by mast cell. Located in plasma membrane. Is expressed in cerebral cortex ventricular layer; cortical plate; and testis. Orthologous to human CD300A (CD300a molecule). PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased susceptibility to cecal ligation and puncture with increased production of chemoattractants by mast cells. [provided by MGI curators] |