Primary Identifier | MGI:2442359 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 246746 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables several functions, including interleukin-4 receptor binding activity; phosphatidylserine binding activity; and virus receptor activity. Involved in several processes, including interleukin-13-mediated signaling pathway; positive regulation of interleukin-4-mediated signaling pathway; and regulation of apoptotic cell clearance. Acts upstream of or within osteoclast differentiation. Predicted to be active in plasma membrane. Is expressed in early conceptus; embryo; and retina. Orthologous to human CD300LF (CD300 molecule like family member f). PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased severity of experimental autoimmune encephalomyelitis with increased demyelination. [provided by MGI curators] |