Primary Identifier | MGI:2384159 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 260302 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable protein transporter activity; small GTPase binding activity; and ubiquitin binding activity. Acts upstream of or within positive regulation of protein catabolic process and protein localization to lysosome. Predicted to be located in Golgi apparatus; endosome; and lysosome. Predicted to be part of protein-containing complex. Predicted to be active in trans-Golgi network. Is expressed in several structures, including heart; liver; lung; metanephros; and white fat. Orthologous to human GGA3 (golgi associated, gamma adaptin ear containing, ARF binding protein 3). PHENOTYPE: Mice homozygous for a gene-trapped allele display decreased birth weight, slow postnatal weight gain, hypoglycemia, increased plasma levels of acid hydrolases, and partial neonatal lethality. [provided by MGI curators] |