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Protein Coding Gene : H3f3b H3.3 histone B

Primary Identifier  MGI:1101768 Organism  mouse, laboratory
Chromosome  11 NCBI Gene Number  15081
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; RNA polymerase II core promoter sequence-specific DNA binding activity; and nucleosomal DNA binding activity. Acts upstream of or within several processes, including constitutive heterochromatin formation; germ cell development; and regulation of chromosome organization. Located in nucleus. Is expressed in several structures, including alimentary system; brain; eye; genitourinary system; and leg muscle. Orthologous to human H3-3A (H3.3 histone A) and H3-3B (H3.3 histone B).
PHENOTYPE: Mice heterozygous for a reporter allele exhibit reduced body size and male infertility due to failure of spermiogenesis. [provided by MGI curators]
  • synonyms:
  • H3.3B,
  • H3.3 histone B,
  • H3f3b,
  • 9430068D06Rik,
  • MGI:1926214,
  • RIKEN cDNA 9430068D06 gene,
  • H3-3b

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

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0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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0 Driver For