Primary Identifier | MGI:107507 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 14027 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable structural molecule activity. Acts upstream of or within regulation of antibacterial peptide production. Is active in cornified envelope. Orthologous to human EVPL (envoplakin). PHENOTYPE: Mice homozygous for a targeted deletion of this gene are viable and fertile. Surprisingly, cornified envelope assembly is not inhibited and adult homozygotes show no obvious pathological phenotype in skin or other epithelia, despite a slight delay in barrier acquisition during embryonic development. [provided by MGI curators] |