Primary Identifier | MGI:107553 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 20446 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity. Predicted to be involved in protein O-linked glycosylation and protein sialylation. Predicted to be located in Golgi membrane. Is expressed in several structures, including alimentary system; genitourinary system; hemolymphoid system gland; lung; and mammary gland. Orthologous to human ST6GALNAC2 (ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 2). PHENOTYPE: Mice homozygous for a knockout allele exhibit decreased body weight, decreased IgQ, increased B cell proliferation, increased pre-B cell number, abnormal erythropoiesis, increased ALT, decreased creatinine level and prominent spleen germinal center. [provided by MGI curators] |