Primary Identifier | MGI:1858910 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 107817 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables RNA binding activity; identical protein binding activity; and signaling receptor activity. Involved in several processes, including negative regulation of protein homooligomerization; regulation of mRNA splicing, via spliceosome; and sprouting angiogenesis. Acts upstream of or within several processes, including circulatory system development; hemopoiesis; and recognition of apoptotic cell. Located in cytosol; nuclear lumen; and plasma membrane. Part of ribonucleoprotein complex. Is active in nucleus. Is expressed in several structures, including brain; gonad; hemolymphoid system gland; sensory organ; and tooth. Orthologous to human JMJD6 (jumonji domain containing 6, arginine demethylase and lysine hydroxylase). PHENOTYPE: Mice homozygous for disruptions in this gene show perinatal lethality. Abnormalities are observed in the nervous. respiratory, cardiovascular, digestive, renal, hematopoietic, and immune systems. [provided by MGI curators] |