| Primary Identifier | MGI:1203517 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 11799 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable several functions, including cysteine-type endopeptidase inhibitor activity involved in apoptotic process; protein dimerization activity; and small GTPase binding activity. Involved in meiosis I and negative regulation of apoptotic process. Acts upstream of or within several processes, including negative regulation of neuron apoptotic process; regulation of insulin secretion involved in cellular response to glucose stimulus; and regulation of type B pancreatic cell proliferation. Located in cytoplasm. Is active in chromosome, centromeric region. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in prostate cancer; pulmonary hypertension; and transitional cell carcinoma. Orthologous to human BIRC5 (baculoviral IAP repeat containing 5). PHENOTYPE: Homozygous null mutants die during early embryonic development. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
