Primary Identifier | MGI:99554 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 19039 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable scavenger receptor activity. Predicted to be involved in cell adhesion and vesicle-mediated transport. Located in extracellular space. Is expressed in several structures, including brain; genitourinary system; gut; integumental system; and liver and biliary system. Orthologous to human LGALS3BP (galectin 3 binding protein). PHENOTYPE: Homozygous mutants are more susceptible to bacterial infection and overproduce IL-12, interferon-gamma and TNF-alpha. [provided by MGI curators] |