| Primary Identifier | MGI:107440 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 12009 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable protein homodimerization activity. Acts upstream of or within cilium organization and spermatid development. Located in several cellular components, including acrosomal vesicle; centriolar satellite; and sperm head-tail coupling apparatus. Orthologous to human CEP131 (centrosomal protein 131). PHENOTYPE: Mice homozygous for a null allele exhibit partial preweaning lethality with no apparent defects in cilia formation or function. However, homozygotes display complete male infertility associated with spermiogenesis arrest, severe flagellar defects, and teratozoospermia. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
