Primary Identifier | MGI:1919135 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 71885 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable DNA binding activity. Predicted to be involved in interstrand cross-link repair. Predicted to be located in chromatin and cytosol. Predicted to be part of Fanconi anaemia nuclear complex. Predicted to be active in nucleoplasm. Is expressed in bladder; bone; nervous system; rib; and tail paraxial mesenchyme. Orthologous to human FAAP100 (FA core complex associated protein 100). PHENOTYPE: Mice homozygous for a null allele exhibit primordial germ cell loss at E9.5 associated with increased DNA damage and apoptosis. [provided by MGI curators] |