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Protein Coding Gene : Mcrip1 MAPK regulated corepressor interacting protein 1
Primary Identifier  MGI:2384752 Organism  mouse, laboratory
Chromosome  11 NCBI Gene Number  192173
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to be involved in regulation of epithelial to mesenchymal transition. Predicted to be located in cytoplasmic stress granule and nucleus. Is expressed in alveolus epithelium; lung; and lung epithelium. Orthologous to human MCRIP1 (MAPK regulated corepressor interacting protein 1).
PHENOTYPE: Most mice homozygous for a knock-out allele die in the neonatal stage due to atelectasis and respiratory failure associated with decreased surfactant secretion and abnormal alveolar lamellar body morphology. [provided by MGI curators]
  • synonyms:
  • family with sequence similarity 195, member B,
  • cDNA sequence BC003940,
  • MGI:5897470,
  • Fam195b,
  • BC003940,
  • MAPK regulated corepressor interacting protein 1,
  • Mcrip1
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