| Primary Identifier | MGI:2180784 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 170758 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable several functions, including GTP binding activity; GTPase activity; and calcium-dependent protein binding activity. Involved in regulation of postsynapse assembly. Acts upstream of or within several processes, including GABAergic synaptic transmission; neuron development; and regulation of neuron maturation. Is active in glutamatergic synapse and postsynapse. Is expressed in brain and genitourinary system. Orthologous to human RAC3 (Rac family small GTPase 3). PHENOTYPE: Homozygous null mice display decreased stride length and impaired thermal nociception, but have improved motor learning and retention of motor behaviors and normal brain morphology. Homozygous KO reduces susceptibility to tumorigenesis in intestinal adenoma-susceptible mice. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
