Primary Identifier | MGI:1355272 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 104318 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables protein kinase activity. Involved in several processes, including circadian regulation of gene expression; midbrain dopaminergic neuron differentiation; and positive regulation of proteasomal ubiquitin-dependent protein catabolic process. Acts upstream of or within non-motile cilium assembly. Located in nucleus. Is expressed in several structures, including branchial arch; central nervous system; facial prominence ectoderm; foregut; and genitourinary system. Used to study attention deficit hyperactivity disorder. Human ortholog(s) of this gene implicated in advanced sleep phase syndrome 2. Orthologous to human CSNK1D (casein kinase 1 delta). PHENOTYPE: Homozygous null mice die 1.5 to 5 days after birth and fetal weight is significantly smaller than controls. [provided by MGI curators] |