| Primary Identifier | MGI:105066 | Organism | mouse, laboratory |
| Chromosome | 12 | NCBI Gene Number | 19325 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable GDP-dissociation inhibitor binding activity; guanyl ribonucleotide binding activity; and myosin V binding activity. Involved in cellular response to insulin stimulus; protein localization to plasma membrane; and vesicle-mediated transport. Located in Golgi apparatus; cilium; and perinuclear region of cytoplasm. Is expressed in several structures, including brain; liver; and small intestine. Orthologous to human RAB10 (RAB10, member RAS oncogene family). PHENOTYPE: Mice homozygous for a knock-out allele exhibit embryonic growth and development at E7.5 with reduced cell proliferation and complete resorption by E9.5. Mice homozygous for a conditional allele activated in hepatocytes exhibit hepatic insulin resistance. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
