Primary Identifier | MGI:2443036 | Organism | mouse, laboratory |
Chromosome | 12 | NCBI Gene Number | 217378 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables GTPase activity. Involved in positive regulation of ERK1 and ERK2 cascade. Located in nucleus. Orthologous to human DNAJC27 (DnaJ heat shock protein family (Hsp40) member C27). PHENOTYPE: Mice homozygous for a gene trapped allele exhibit decreased incidence, multiplicity and tumor burden in an AOM/DSS-induced colonic carcinogenesis model. [provided by MGI curators] |