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Protein Coding Gene : Itsn2 intersectin 2

Primary Identifier  MGI:1338049 Organism  mouse, laboratory
Chromosome  12 NCBI Gene Number  20403
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable molecular adaptor activity. Acts upstream of or within cell-cell signaling and endocytosis. Is active in cytosol. Is expressed in several structures, including endocrine gland; hemolymphoid system; ileum; male reproductive gland or organ; and nervous system. Used to study nephrotic syndrome. Orthologous to human ITSN2 (intersectin 2).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit normal brain morphology and function and behavior. Mice lacking the long isoform exhibit delayed recovery from LPS-induced kidney injury. [provided by MGI curators]
  • synonyms:
  • Sh3d1B,
  • Itsn2,
  • expressed sequence AI327390,
  • SH3 domain protein 1B,
  • intersectin 2,
  • Eh domain, SH3 domain regulator of endocytosis 2,
  • mKIAA1256,
  • Ese2,
  • AI327390,
  • Sh3p18,
  • MGI:2144799

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

9 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For