| Primary Identifier | MGI:1860483 | Organism | mouse, laboratory |
| Chromosome | 12 | NCBI Gene Number | 56184 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables DNA-binding transcription activator activity, RNA polymerase II-specific and chromatin binding activity. Acts upstream of or within segment specification and somitogenesis. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Is expressed in several structures, including allantois; embryo mesoderm; primitive streak; tail; and unsegmented mesenchyme. Orthologous to human MSGN1 (mesogenin 1). PHENOTYPE: Homozygous null mutants die during gestation, displaying severe disruption of somitogenesis and enlargement of the tailbud. Later in development, homozygotes show a striking absence of all trunk and tail skeletal muscle and axial skeleton, whereas the hindlimb skeleton remains unaffected. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
