|  Help  |  About  |  Contact Us

Protein Coding Gene : Gen1 GEN1, Holliday junction 5' flap endonuclease

Primary Identifier  MGI:2443149 Organism  mouse, laboratory
Chromosome  12 NCBI Gene Number  209334
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable several functions, including DNA endonuclease activity; magnesium ion binding activity; and protein homodimerization activity. Predicted to be involved in DNA metabolic process and regulation of cell cycle process. Predicted to be located in centrosome. Is expressed in embryo; heart; metanephros; nephric duct; and neural tube. Orthologous to human GEN1 (GEN1 Holliday junction 5' flap endonuclease).
PHENOTYPE: Mice homozygous for a hypomorphic allele exhibit abnormal kidney and urinary tract development. [provided by MGI curators]
  • synonyms:
  • GEN1, Holliday junction 5' flap endonuclease,
  • 5830483C08Rik,
  • Gen1,
  • RIKEN cDNA 5830483C08 gene

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

7 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For