Primary Identifier | MGI:2149712 | Organism | mouse, laboratory |
Chromosome | 12 | NCBI Gene Number | 268527 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to be involved in morphogenesis of an epithelium. Predicted to be located in membrane. Is expressed in several structures, including central nervous system; genitourinary system; incisor; retina nuclear layer; and tail unsegmented mesenchyme. Orthologous to human GREB1 (growth regulating estrogen receptor binding 1). PHENOTYPE: Homozygous null females are subfertile with decreased litter sizes, have impaired embryo implantation and uterine receptivity due to impaired uterine responses to steroid hormones. [provided by MGI curators] |