Primary Identifier | MGI:1289332 | Organism | mouse, laboratory |
Chromosome | 12 | NCBI Gene Number | 380752 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to be involved in several processes, including endocytic recycling; positive regulation of intracellular transport; and regulation of insulin secretion. Predicted to be located in trans-Golgi network. Predicted to be part of EARP complex and GARP complex. Is expressed in hippocampus; liver; neural retina; and olfactory epithelium. Orthologous to human EIPR1 (EARP complex and GARP complex interacting protein 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased embryo size, a rudimentary egg cylinder, failure of primitive streak formation, absent primitive node and head folds, failure to gastrulate, and complete embryonic lethality prior to organogenesis. [provided by MGI curators] |