| Primary Identifier | MGI:894659 | Organism | mouse, laboratory |
| Chromosome | 12 | NCBI Gene Number | 73389 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in negative regulation of lipid transport and negative regulation of reactive oxygen species biosynthetic process. Predicted to be located in nuclear speck. Predicted to be active in nucleus. Is expressed in several structures, including brain; early conceptus; genitourinary system; gut; and neural retina. Orthologous to human HBP1 (HMG-box transcription factor 1). PHENOTYPE: Mice heterozygous for a gene trapped allele have behavioral abnormalities and show alterations in leukocyte, platelet and NK cell number, blood urea nitrogen levels, and circulating amylase and calcium levels. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
