| Primary Identifier | MGI:2661416 | Organism | mouse, laboratory |
| Chromosome | 12 | NCBI Gene Number | 217463 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable phosphatidylinositol binding activity. Predicted to be involved in intracellular protein transport and positive regulation of GTPase activity. Predicted to be located in early endosome membrane. Predicted to be active in early endosome. Is expressed in embryo. Orthologous to human SNX13 (sorting nexin 13). PHENOTYPE: Homozygous null mice are growth retarded and die at midgestation with defects in neural tube closure, vasculogenesis and placental development. Mutant visceral yolk sac endoderm cells exhibit altered endocytic compartments, abundant autophagic vacuoles and mislocalization of endocytic markers. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
