Primary Identifier | MGI:2442474 | Organism | mouse, laboratory |
Chromosome | 12 | NCBI Gene Number | 217480 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables ATP-dependent diacylglycerol kinase activity. Involved in modulation of chemical synaptic transmission and regulation of postsynapse organization. Acts upstream of or within response to bacterium. Located in plasma membrane. Is active in Schaffer collateral - CA1 synapse and glutamatergic synapse. Is expressed in anterior abdominal wall musculature; nervous system; retina; and urinary system. Orthologous to human DGKB (diacylglycerol kinase beta). PHENOTYPE: Mice homozygous for a transposon distruption have defects in long term potentiation, synapase morphology, and in spatial reference and working memory. [provided by MGI curators] |