Primary Identifier | MGI:1316717 | Organism | mouse, laboratory |
Chromosome | 12 | NCBI Gene Number | 15982 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable RNA polymerase II-specific DNA-binding transcription factor binding activity. Acts upstream of or within several processes, including muscle cell differentiation; negative regulation of axonogenesis; and skeletal muscle tissue regeneration. Located in nucleus and sarcoplasm. Is expressed in several structures, including extraembryonic component; liver and biliary system; nasal cavity epithelium; nervous system; and tooth. Orthologous to human IFRD1 (interferon related developmental regulator 1). PHENOTYPE: Homozygous null mice display impaired muscle regeneration and myogenic differentiation and decreased body weight in older mice. [provided by MGI curators] |