Primary Identifier | MGI:106036 | Organism | mouse, laboratory |
Chromosome | 12 | NCBI Gene Number | 16981 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within positive regulation of synapse assembly. Predicted to be located in membrane. Predicted to be part of clathrin adaptor complex. Predicted to be active in extracellular matrix and extracellular space. Is expressed in several structures, including alimentary system; central nervous system; peripheral nervous system ganglion; respiratory system; and sensory organ. Orthologous to human LRRN3 (leucine rich repeat neuronal 3). PHENOTYPE: Homozygous null mutant mice exhibited increased mean percent body fat and male homozygous mutant mice exhibited enhanced glucose tolerance when compared with controls. [provided by MGI curators] |