Primary Identifier | MGI:1309478 | Organism | mouse, laboratory |
Chromosome | 12 | NCBI Gene Number | 217578 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable DNA binding activity. Involved in positive regulation of DNA replication. Located in nuclear chromosome and pericentric heterochromatin. Is expressed in several structures, including central nervous system; early conceptus; and genitourinary system. Orthologous to human BAZ1A (bromodomain adjacent to zinc finger domain 1A). PHENOTYPE: Mice homozygous for a knock-out allele are viable and able to repair meiotic double-strand breaks but exhibit teratospermia, oligospermia, asthenospermia, and male infertility due to impaired spermiogenesis. [provided by MGI curators] |