Primary Identifier | MGI:1914114 | Organism | mouse, laboratory |
Chromosome | 12 | NCBI Gene Number | 66864 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable extracellular matrix binding activity and extracellular matrix protein binding activity. Involved in cell migration involved in sprouting angiogenesis. Acts upstream of or within with a positive effect on vascular endothelial growth factor receptor-3 signaling pathway. Acts upstream of or within with a negative effect on vascular endothelial growth factor receptor-2 signaling pathway. Acts upstream of or within lymphangiogenesis and sprouting angiogenesis. Located in collagen-containing extracellular matrix. Is expressed in bladder; central nervous system; embryo mesenchyme; and head blood vessel. Orthologous to human CLEC14A (C-type lectin domain containing 14A). PHENOTYPE: No notable pheontype was detected in a high-throughput screen of homozygous mutant mice. [provided by MGI curators] |