| Primary Identifier | MGI:2444354 | Organism | mouse, laboratory |
| Chromosome | 12 | NCBI Gene Number | 238247 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable transcription cis-regulatory region binding activity. Acts upstream of or within several processes, including erythrocyte development; establishment of Sertoli cell barrier; and regulation of gene expression. Predicted to be located in nucleoplasm and plasma membrane. Predicted to be part of transcription repressor complex. Predicted to be active in nucleus. Used to study acute myeloid leukemia. Orthologous to human ARID4A (AT-rich interaction domain 4A). PHENOTYPE: Mice homozygous for a knock-out allele exhibit altered DNA methylation patterns, disrupted hematopoiesis and a portion develop acute myeloid leukemia. Mice homozygous for an ENU-induced allele exhibit short tibia and femur. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
