| Primary Identifier | MGI:1858901 | Organism | mouse, laboratory |
| Chromosome | 12 | NCBI Gene Number | 53618 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables alpha-(1->6)-fucosyltransferase activity. Acts upstream of or within several processes, including N-glycan fucosylation; cell surface receptor signaling pathway; and fibroblast migration. Predicted to be located in Golgi cisterna membrane. Is expressed in telencephalon. Used to study pulmonary emphysema. Orthologous to human FUT8 (fucosyltransferase 8). PHENOTYPE: Homozygous null mutation of this gene results in partial postnatal lethality, growth retardation, and progressive emphysema-like changes that include enlarged alveoli, increased lung capacity and compliance, and alveolar cell apoptosis. Postnatal survival is sensitive to genetic background. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
